SB 10.74.53
duryodhanam rte papam
kalim kuru-kulamayam
yo na sehe sriyam sphitam
drstva pandu-sutasya tam
Translation:
[All were satisfied] except sinful Duryodhana, the personification of the age of quarrel and the disease of the Kuru dynasty. He could not bear to see the flourishing opulence of the son of Pandu.
Purport:
Srila Prabhupada writes: “Duryodhana by nature was very envious because of his sinful life, and he appeared in the dynasty of the Kurus as a chronic disease personified in order to destroy the whole family.” Srila Sridhara Svami mentions that Duryodhana hated pure religious principles.