ekadasami manaso vikarah
sahasrasah satasah kotisas ca
ksetrajñato na mitho na svatah syuh
Translation by His Divine Grace A. C. Bhaktivedanta Swami Srila Prabhupada:
The physical elements, nature, the original cause, culture, destiny and the time element are all material causes. Agitated by these material causes, the eleven functions transform into hundreds of functions and then into thousands and then into millions. But all these transformations do not take place automatically by mutual combination. Rather, they are under the direction of the Supreme Personality of Godhead.
Purport by His Divine Grace A. C. Bhaktivedanta Swami Srila Prabhupada:
One should not think that all the interactions of the physical elements, gross and subtle, that cause the transformation of mind and consciousness are working independently. They are under the direction of the Supreme Personality of Godhead. In Bhagavad-gita (15.15), Krsna says that the Lord is situated in everyone’s heart (sarvasya caham hrdi sannivisto mattah smrtir jñanam apohanam ca). As mentioned herein, Supersoul (ksetrajña) is directing everything. The living entity is also ksetrajña, but the supreme ksetrajña is the Supreme Personality of Godhead. He is the witness and order giver. Under His direction, everything takes place. The different inclinations of the living entity are created by his own nature or his expectations, and he is trained by the Supreme Personality of Godhead through the agency of material nature. The body, nature and the physical elements are under the direction of the Supreme Personality of Godhead. They do not function automatically. Nature is neither independent nor automatic. As confirmed in Bhagavad-gita, the Supreme Personality of Godhead is behind nature.
“This material nature is working under My direction, O son of Kunti, and it is producing all moving and unmoving beings. By its rule this manifestation is created and annihilated again and again.” (Bg. 9.10)