tam ahagadhaya vaca
kasmalam samayann iva
Translation by His Divine Grace A. C. Bhaktivedanta Swami Srila Prabhupada:
The Lord saw that Brahma was very anxious about the planning and construction of the different planetary systems and was depressed upon seeing the devastating water. He could understand the intention of Brahma, and thus He spoke in deep, thoughtful words, removing all the illusion that had arisen.
Purport by His Divine Grace A. C. Bhaktivedanta Swami Srila Prabhupada:
The devastating water was so fearful that even Brahma was perturbed at its appearance and became very anxious about how to situate the different planetary systems in outer space to accommodate the different kinds of living entities, such as the human beings, those lower than the human beings, and the superhuman beings. All the planets in the universe are situated according to the different grades of living entities under the influence of the modes of material nature. There are three modes of material nature, and when they are mixed with one another they become nine. When the nine are mixed they become eighty-one, and the eighty-one also become mixed, and thus we ultimately do not know how the delusion increases and increases. Lord Brahma had to accommodate different places and situations for the requisite bodies of the conditioned souls. The task was meant only for Brahma, and no one in the universe can even understand how difficult it was. But by the grace of the Lord, Brahma was able to execute the tremendous task so perfectly that everyone is amazed to see the workmanship of the vidhata, or the regulator.