ittham karma-gatir gacchan
pralayav asnute ’vasah
Translation by His Divine Grace A. C. Bhaktivedanta Swami Srila Prabhupada:
Thus the conditioned living entity is forced to experience repeated birth and death. Impelled by the reactions of his own activities, he helplessly wanders from one inauspicious situation to another, suffering from the moment of creation until the time of cosmic annihilation.
Purport by His Divine Grace A. C. Bhaktivedanta Swami Srila Prabhupada:
According to Srila Madhvacarya, after hearing that the living entity is repeatedly subjected to birth and death within the material world, if one still considers such a helpless entity equal to God in all respects one will surely fall into the darkest regions of the universe, from which it is difficult to rise.